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Generic Name: sorafenib (sor a FEN ib)
Brand Names: NexAVAR
Minimum amount: 60 tablets.
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NEXAVAR is an anticancer medicine used to treat a certain type of liver, kidney or thyroid cancer called:
- Hepatocellular carcinoma (HCC, a type of liver cancer), when it cannot be treated with surgery
- Renal cell carcinoma (RCC, a type of kidney cancer)
- Differentiated thyroid carcinoma (DTC, a type of thyroid cancer) that can no longer be treated with radioactive iodine and is progressing
Nexavar also known as sorafenib is a cancer medication that interferes with the growth and spread of cancer cells in the body.
Nexavar is used to treat liver cancer, thyroid cancer, or a type of kidney cancer called advanced renal cell carcinoma.
Some of the side effects of Nexavar
Nexavar has a lot of side effects and so you should stop using Nexavar immediately and call your doctor at once if you have:
- mouth sores;
- blood in your urine or stools, coughing up blood or vomit that looks like coffee grounds;
- heavy menstrual periods, easy bruising, unusual bleeding, or any bleeding that will not stop;
- pale skin, feeling light-headed, rapid heart rate, trouble concentrating;
- dry cough, wheezing;
- chest pain and severe dizziness, fainting, sweating, swelling, rapid weight gain, feeling short of breath (even with mild exertion);
- rash, blisters, oozing, or severe pain in the palms of your hands or the soles of your feet;
- upper stomach pain, itching, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes);
- sudden weight loss, increased appetite, trouble sleeping, increased bowel movements, feeling hot, feeling nervous or anxious, swelling in your neck (goiter);
- dangerously high blood pressure (severe headache, blurred vision, buzzing in your ears, confusion, uneven heartbeats, seizure); or
- severe skin reaction — fever, sore throat, swelling in your face or tongue, burning in your eyes, skin pain, followed by a red or purple skin rash that spreads (especially in the face or upper body) and causes blistering and peeling.
Common Nexavar side effects may include:
- tired feeling;
- vomiting, diarrhea, mild stomach pain;
- mild itching or rash; or
- weight loss, thinning hair.
Instructions to caregivers administering Nexavar
Sorafenib can pass into body fluids (urine, feces, vomit). Caregivers should wear rubber gloves while cleaning up a patient’s body fluids, handling contaminated trash or laundry or changing diapers. Wash hands before and after removing gloves. Wash soiled clothing and linens separately from other laundry.
NEXAVAR has not been studied in children.
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